Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
USERS' SCORE
Moderately Good
Based on 72 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
Inositol
500 mg
**

Top Medical Research Studies

9
IP6 improves cholesterol levels
We examined the effects of inositol hexakisphosphate (IP6) and myo-inositol on high cholesterol in rats. In our study, we found that dietary IP6 effectively reduced increased cholesterol levels caused by a specific chemical exposure, while myo-inositol did not show significant benefits.

Additionally, IP6 also contributed to body weight gain, regardless of other dietary factors. Overall, while both inositol types helped prevent fatty liver, only IP6 demonstrated a clear advantage in managing hypercholesterolemia.
Read More
9
Inositol boosts growth and health
We explored how inositol affects growth performance and cholesterol levels in largemouth bass through a systematic diet study. By preparing six different diets with varying inositol concentrations, we fed the fish for eight weeks and closely monitored their progress. The results showed that our group consuming 250 mg/kg of inositol enjoyed significantly better weight gain, growth rates, and feed efficiency compared to the control group.

Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.

Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.

Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
Read More
9
D--Inositol reduces cholesterol levels
We examined how D--Inositol (DCI), a natural compound found in many living organisms, influences high cholesterol and obesity, especially when combined with a high-fat diet. In our study involving mice over a 12-week period, we observed that DCI supplementation led to noticeable reductions in body weight, triglycerides, total cholesterol, insulin, and fasting glucose levels when given at doses of 50 and 100 mg per kg daily.

The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.

Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
Read More

Most Useful Reviews

9
Effective quality supplement
132 people found this helpful
Inositol effectively normalises blood cholesterol levels. Super quality.
Read More
9
Restores ovulation
63 people found this helpful
After suffering from polycystic ovary syndrome and missing ovulation, I was desperate and tried numerous supplements. Discovering inositol was a breakthrough; I started a regimen of 1 tablet twice daily. Within a month, I witnessed remarkable changes—my ovaries appeared appropriate in size, follicles were countable, and above all, I finally experienced ovulation! For those grappling with similar issues, I highly recommend giving this vitamin a try!
Read More
8
Regulates menstrual cycle
63 people found this helpful
This is the second time using this vegetarian alternative to metformin for polycystic ovary syndrome (PCOS). After three months, it helps regulate my menstrual cycle and manage weight without affecting my appetite. I take two pills after heavy meals because it reduces sugar levels. Drink plenty of water afterwards. The ingredients are vegetarian and do no harm. The capsules are easy to take, and I highly recommend this for those looking for a gentle yet effective option.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 10 Researches
8.3
  • All Researches
9
Inositol boosts growth and health
We explored how inositol affects growth performance and cholesterol levels in largemouth bass through a systematic diet study. By preparing six different diets with varying inositol concentrations, we fed the fish for eight weeks and closely monitored their progress. The results showed that our group consuming 250 mg/kg of inositol enjoyed significantly better weight gain, growth rates, and feed efficiency compared to the control group.

Interestingly, as we increased the inositol levels, we noticed a rise in serum triglycerides and cholesterol, particularly peaking in the 250 mg/kg group. It appeared that while inositol helped improve overall growth, it also influenced cholesterol levels in a complex way. However, the high-density lipoprotein cholesterol (HDL-C), often considered "good" cholesterol, remained unaffected across all treatment groups.

Furthermore, our analysis revealed that inositol supplementation not only reduced fat deposition in the liver but also enhanced the fish's antioxidant capacity by lowering harmful enzymes and increasing beneficial antioxidant markers. This suggests that while inositol modified cholesterol dynamics, it also supported the general health and performance of the fish.

Overall, the findings indicate that dietary inositol can significantly improve growth and antioxidant capacity in largemouth bass, with an optimal dosage around 250 mg/kg to harness these benefits effectively.
Read More
9
Food supplement aids cholesterol management
We tested the effectiveness of a food supplement combining glucomannan, D-chiro-inositol, blume, and inulin in managing high cholesterol levels among individuals with metabolic syndrome. Fifty-eight participants, each dealing with either type 2 diabetes or impaired glucose tolerance, took this supplement daily for four months alongside their metformin medication.

Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).

Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
Read More
9
D--Inositol reduces cholesterol levels
We examined how D--Inositol (DCI), a natural compound found in many living organisms, influences high cholesterol and obesity, especially when combined with a high-fat diet. In our study involving mice over a 12-week period, we observed that DCI supplementation led to noticeable reductions in body weight, triglycerides, total cholesterol, insulin, and fasting glucose levels when given at doses of 50 and 100 mg per kg daily.

The findings were encouraging as DCI not only diminished body weight but also helped lower fat accumulation in the liver and fat tissue. Importantly, we noted a significant increase in serum adiponectin levels, a beneficial hormone linked to improved lipid metabolism. This increase was accompanied by enhanced activity of adiponectin receptors in the liver, which play a key role in regulating fat and energy metabolism.

Additionally, DCI was shown to activate a critical pathway involving AMPKα and PPARs, further promoting healthy fat management in the body. These results suggest that DCI could be a valuable ally in addressing cholesterol and obesity issues, potentially through its influence on adiponectin synthesis and its related metabolic pathways.
Read More
9
IP6 improves cholesterol levels
We examined the effects of inositol hexakisphosphate (IP6) and myo-inositol on high cholesterol in rats. In our study, we found that dietary IP6 effectively reduced increased cholesterol levels caused by a specific chemical exposure, while myo-inositol did not show significant benefits.

Additionally, IP6 also contributed to body weight gain, regardless of other dietary factors. Overall, while both inositol types helped prevent fatty liver, only IP6 demonstrated a clear advantage in managing hypercholesterolemia.
Read More
8
Myo-inositol reduces cholesterol levels
We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.

In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.

Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 72 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective quality supplement
132 people found this helpful
Inositol effectively normalises blood cholesterol levels. Super quality.
Read More
9
Restores ovulation
63 people found this helpful
After suffering from polycystic ovary syndrome and missing ovulation, I was desperate and tried numerous supplements. Discovering inositol was a breakthrough; I started a regimen of 1 tablet twice daily. Within a month, I witnessed remarkable changes—my ovaries appeared appropriate in size, follicles were countable, and above all, I finally experienced ovulation! For those grappling with similar issues, I highly recommend giving this vitamin a try!
Read More
8
Regulates menstrual cycle
63 people found this helpful
This is the second time using this vegetarian alternative to metformin for polycystic ovary syndrome (PCOS). After three months, it helps regulate my menstrual cycle and manage weight without affecting my appetite. I take two pills after heavy meals because it reduces sugar levels. Drink plenty of water afterwards. The ingredients are vegetarian and do no harm. The capsules are easy to take, and I highly recommend this for those looking for a gentle yet effective option.
Read More
9
Impressive cyst treatment
31 people found this helpful
Inositol was effective for my ovarian cysts, and although the price is high, I found it at a great price online. After taking it for two and a half months, my hormone levels significantly decreased. It’s an alternative to Glucophage with similar effectiveness and without the unpleasant side effects. I recommend drinking plenty of water while taking it.
Read More
9
Increases energy levels
23 people found this helpful
This Now Inositol has been a lifesaver for my PCOS! Previously struggling with terrible dysmenorrhea and persistent fatigue, I began taking it daily. Within a week, I noticed a significant increase in my energy levels and a decrease in bloating. After a month, my cravings for sugar diminished drastically, and I've lost several pounds. I combined this with dietary adjustments and home workouts, but the improvement in my weight loss has been remarkable since starting the supplement.
Read More

Frequently Asked Questions

7.5
Improves metabolism
13 people found this helpful
The quality of this supplement is commendable! After two weeks of taking it, I noticed improvements in my acne and metabolism, leading to weight loss and normalising fat metabolism. Inositol and folic acid enhance each other's absorption, making it ideal for menstrual cycle and ovulation issues, including PCOS. I’ve been satisfied with it every time I've used it.
9
Liver function normalised
11 people found this helpful
Please… I purchased this for anxiety regarding liver function and for pregnancy. It's less than half the price of fertility supplements I've been taking. A follow-up blood sample today showed that my liver function had normalised, good cholesterol had risen, and bad cholesterol had fallen to a lower normal limit, leaving the doctor amazed. Even though my eating and drinking habits haven't changed, taking it orally significantly lowered my bad cholesterol levels. I'm very happy with these results and will likely continue taking it!
9
Cholesterol significantly lowered
6 people found this helpful
The cholesterol level was exceptionally high, likely due to heredity. However, after a year of continued use, it dropped by approximately 80! I attribute this improvement to the supplement, as my eating habits and exercise routines have not changed significantly.
9
Restores ovulation
63 people found this helpful
After suffering from polycystic ovary syndrome and missing ovulation, I was desperate and tried numerous supplements. Discovering inositol was a breakthrough; I started a regimen of 1 tablet twice daily. Within a month, I witnessed remarkable changes—my ovaries appeared appropriate in size, follicles were countable, and above all, I finally experienced ovulation! For those grappling with similar issues, I highly recommend giving this vitamin a try!
9
Effective for PCOS
11 people found this helpful
Inositol has been my salvation amidst diabetes and PCOS challenges. My testosterone levels were alarmingly high, but after switching to a different inositol product, I saw significant reductions—my levels decreased from 5 to 2! I sincerely recommend it for those facing similar issues.
9
Increases energy levels
23 people found this helpful
This Now Inositol has been a lifesaver for my PCOS! Previously struggling with terrible dysmenorrhea and persistent fatigue, I began taking it daily. Within a week, I noticed a significant increase in my energy levels and a decrease in bloating. After a month, my cravings for sugar diminished drastically, and I've lost several pounds. I combined this with dietary adjustments and home workouts, but the improvement in my weight loss has been remarkable since starting the supplement.
9
Normal cholesterol levels
15 people found this helpful
This is a very potent helper in reducing cholesterol. Together with a balanced diet, it has successfully brought my husband’s cholesterol to a normal level. Highly effective!
7.5
Improved metabolism
3 people found this helpful
The quality of the drug is excellent! After just two weeks, the appearance of my acne decreased, and my metabolism improved, contributing to weight loss by normalising fat metabolism. The dosage is great. Inositol and folic acid enhance each other's absorption. It lowers cholesterol and glucose levels when used continuously, which is vital for managing my high cholesterol.
8
Normalised cholesterol levels
4 people found this helpful
I was advised by my doctor to normalise hormonal levels with a daily dosage of 1000mg of inositol and increase folic acid. Consistency over a year is essential. Inositol also enhances beauty by promoting hair and nail growth, normalises fat metabolism, and reduces cholesterol levels while having no contraindications.
9
Significant weight loss
5 people found this helpful
I have PCOS, and this product has been effective. I’ve reduced my weight from 138 to 128 pounds at 4'11". It has balanced my insulin levels and is vital as I'm prediabetic. A higher dose would be better; I take three pills at once. The quality is good, it's tasteless, and I'm pleased with the results.
9
Food supplement aids cholesterol management
We tested the effectiveness of a food supplement combining glucomannan, D-chiro-inositol, blume, and inulin in managing high cholesterol levels among individuals with metabolic syndrome. Fifty-eight participants, each dealing with either type 2 diabetes or impaired glucose tolerance, took this supplement daily for four months alongside their metformin medication.

Over the course of the study, we observed significant improvements in several key health markers. The participants experienced a marked reduction in their body weight and body mass index (BMI). More importantly for those dealing with high cholesterol, the supplement contributed to noteworthy enhancements in their lipid profiles. Levels of total cholesterol reduced significantly, alongside improvements in triglycerides and low-density lipoprotein (LDL).

Our findings suggest that this food supplement may be a beneficial addition to traditional treatments for managing cholesterol levels and other risk factors associated with metabolic syndrome. This study highlights the potential of inositol as part of a multi-ingredient supplement, although the specific effect of inositol alone wasn't isolated.
8
Inositol and cholesterol management
This study aimed to explore how a combination of myo-inositol and d-chiro-inositol, along with α-lactalbumin, Gymnema sylvestre, and zinc, impacts cholesterol levels in patients with type 2 diabetes mellitus (T2DM).

We evaluated 75 participants who were randomly assigned to either the supplement group or a placebo group. While we found no significant improvements in blood glucose levels between the two groups overall, the results for cholesterol were more promising.

After three months of supplementation, those taking the combination of nutrients experienced a noticeable reduction in total cholesterol and LDL (or bad cholesterol) levels. In a subgroup of patients who kept their diabetes medications unchanged, cholesterol improvements continued to show after six months.

Additionally, members of the supplement group also saw better weight management and enhancements in their HDL (good cholesterol) and triglyceride levels after three months. These findings suggest that combining these specific nutrients could be beneficial in managing cholesterol levels for those with T2DM.
8
Myo-inositol reduces cholesterol levels
We wanted to understand how myo-inositol (MI), a compound found in many foods, influences cholesterol levels and overall metabolic health in db/db mice, a commonly used model for type 2 diabetes. Our findings revealed that providing MI significantly reduced high cholesterol and triglyceride levels in these mice, making a noticeable impact on their lipid profiles.

In addition to lowering cholesterol levels, MI improved insulin resistance, suggesting it might offer a dual benefit for those struggling with metabolic disorders. Interestingly, while MI showed promising effects on cholesterol and glucose levels, it did not help with obesity in the treated mice.

Overall, our study highlights myo-inositol as a potential adjunct therapy for managing high cholesterol and related metabolic challenges in diabetes. These results indicate that incorporating this accessible compound into dietary strategies might benefit patients dealing with these issues.

References

  1. Long L, Huang Q, Song T, Dai Z. Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice. J Appl Biomed. 2024;22:74. doi:10.32725/jab.2024.009
  2. Xu Y, Gong Y, Li S, Zhou Y, Ma Z, et al. Inositol Inclusion Affects Growth, Body Composition, Antioxidant Performance, and Lipid Metabolism of Largemouth Bass (). Aquac Nutr. 2024;2024:9944159. doi:10.1155/2024/9944159
  3. Citarrella R, Chianetta R, Amodeo S, Mirarchi L, Licata A, et al. Effectiveness of a Food Supplement Based on Glucomannan, D-Chiro-Inositol, Blume and Inulin in Patients with Metabolic Syndrome. Nutrients. 2024;16. doi:10.3390/nu16020249
  4. Nani A, Bertuzzi F, Meneghini E, Mion E, Pintaudi B. Combined Inositols, α-Lactalbumin, Gymnema Sylvestre and Zinc Improve the Lipid Metabolic Profile of Patients with Type 2 Diabetes Mellitus: A Randomized Clinical Trial. J Clin Med. 2023;12. doi:10.3390/jcm12247650
  5. Tutunchi H, Arefhosseini S, Ebrahimi-Mameghani M. Clinical effectiveness of α-lipoic acid, myo-inositol and propolis supplementation on metabolic profiles and liver function in obese patients with NAFLD: A randomized controlled clinical trial. Clin Nutr ESPEN. 2023;54:412. doi:10.1016/j.clnesp.2023.02.016
  6. Yang Q, Zhang Y, Li L, Li J, Li Y, et al. D--Inositol facilitates adiponectin biosynthesis and activates the AMPKα/PPARs pathway to inhibit high-fat diet-induced obesity and liver lipid deposition. Food Funct. 2022;13:7192. doi:10.1039/d2fo00869f
  7. Bahadur A, Arora H, Ravi AK, Naithani M, Bahurupi Y, et al. Comparison of Clinical, Metabolic and Hormonal Effects of Metformin Versus Combined Therapy of Metformin With Myoinositol Plus D-Chiro-Inositol in Women With Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Cureus. 2021;13:e15510. doi:10.7759/cureus.15510
  8. Derosa G, D'Angelo A, Vanelli A, Maffioli P. An Evaluation of a Nutraceutical with Berberine, Curcumin, Inositol, Banaba and Chromium Picolinate in Patients with Fasting Dysglycemia. Diabetes Metab Syndr Obes. 2020;13:653. doi:10.2147/DMSO.S232791
  9. Choi MS, Lee MK, Jung UJ, Kim HJ, Do GM, et al. Metabolic response of soy pinitol on lipid-lowering, antioxidant and hepatoprotective action in hamsters fed-high fat and high cholesterol diet. Mol Nutr Food Res. 2009;53:751. doi:10.1002/mnfr.200800241
  10. Okazaki Y, Katayama T. Dietary inositol hexakisphosphate, but not myo-inositol, clearly improves hypercholesterolemia in rats fed casein-type amino acid mixtures and 1,1,1-trichloro-2,2-bis (p-chlorophenyl) ethane. Nutr Res. 2008;28:714. doi:10.1016/j.nutres.2008.07.003
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